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PT-141 (Bremelanotide)



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Buy PT-141 (Bremelanotide) for Sale

PT-141, also known as Bremelanotide, is a synthetic peptide that is similar in structure to the alpha-melanocyte-stimulating hormone (α-MSH). Research has shown that it promotes sexual desire in females with hypoactive sexual desire disorder.

In clinical trials, PT-141 has demonstrated the ability to stimulate penile activity in men with erectile dysfunction. It works by stimulating melanocortin receptors in the brain, which regulate a variety of physiological processes, including sexual arousal.


What is PT-141?

PT-141 is a synthetic peptide analog of alpha-melanocyte-stimulating hormone (alpha-MSH). Alpha-MSH is a naturally occurring hormone that regulates a variety of physiological processes in the body, including sexual arousal, appetite, and melanin production.

PT-141 was originally developed as a potential treatment for both male and female dysfunction. In clinical trials, it has exhibited the ability to treat female sexual dysfunction. Specifically, PT-141 was found to treat hypoactive sexual desire disorder (HSDD) in females. [R]

Clinical trials have reported PT-141 as a promising candidate for further evaluation as a treatment for male erectile dysfunction (ED). This synthetic peptide has demonstrated the ability to induce erectile response in healthy male subjects as well as men with ED. [R]

In the above studies, all doses were well tolerated. No significant changes in blood pressure, heart rate, or electrocardiographic (ECG) parameters were identified. However, at the time of writing, PT-141 is available for purchase for laboratory research use only.


How Does PT-141 Work?

PT-141 works by binding to melanocortin receptors. MCRs are a group of G protein-coupled receptors (GPCRs) found in the skin, brain, and adrenal glands. They play vital roles in regulating sexual behavior, inducing skin pigmentation, and controlling appetite.

Among the 5 MCRs (MC1R to MC5R) in the body, PT-141 has a solid affinity for: [R]

  • MC3R – This melanocortin receptor has been found to regulate sexual function in humans, including the initiation of puberty and sexual behavior. [R]
  • MC4R – MC4R regulates a variety of physiological processes, including sexual function, energy homeostasis, cachexia, and other functions. [R]


PT-141 Research

Multiple clinical and preclinical studies have been conducted to examine the potential effects of PT-141. These studies have mainly examined the effects of this synthetic peptide on female sexual dysfunctions, psychogenic erectile dysfunction in males, and more.

Here are the key findings:


PT-141 and HSDD

Hypoactive sexual desire disorder (HSDD) is a persistent or recurrent absence of sexual desire. It affects about 10% of females in the US and is associated with depression.

In a clinical trial involving postmenopausal women with HSDD, PT-141 treatment brought about a noticeable improvement in sexual desire. More women reported moderate or high sexual desire following PT-141 treatment than those administered placebo. [R]

Subsequently, two phase-3 placebo-controlled trials were conducted to determine the efficacy of PT-141 in premenopausal women with HSDD. Twenty-four weeks of PT-141 treatment significantly improved sexual desire and related distress in the trials’ participants. [R]


PT-141 and FSAD

Female sexual arousal disorder (FSAD) is a condition in which women have little to no interest in sex. And fail to respond physically to sexual stimulation or sexual activity.

In a preliminary study, PT-141 treatment improved arousal and subjective excitement in premenopausal women with FSAD. It was found that both the improvements were clinically significant. This suggests that PT-141 warrants further investigation as a potential treatment for FSAD. [R]


PT-141 and Erectile Dysfunction

In a double-blind placebo-controlled trial, PT-141 treatment induced penile erections in healthy males as well as those with mild-to-moderate ED.

In both studies, the onset of the first erection occurred approximately 30 minutes after administering this synthetic peptide. PT-141 was safely administered and well-tolerated in both studies. No clinically significant changes in vital signs were observed. [R]

Another study found that men with ED who didn’t respond to Viagra experienced adequate erection following PT-141 treatment. Viagra is a drug used to treat ED. Its working mechanism (Viagra targets the vascular system) differs from PT-141, which acts on the brain. [R]


PT-141 and Body Weight

Given that MC4R plays a central role in appetite regulation, a clinical trial was conducted to examine the effects of PT-141’s agonism at MC4R on caloric intake and body weight of obese females.

Results from the trial show that PT-141 induced a significantly greater reduction in body weight after 16 days of treatment versus the placebo. A significantly greater reduction of mean body weight occurred in twice-daily PT-141 subjects versus placebo (1.7 vs 0.9 kg).

It was also reported that a decrease in mean caloric intake drove the reduction in body weight. Those women who were administered PT-141 experienced a reduction of approximately 400 kcal/day throughout the study’s duration. [R]


Frequently Asked Questions

What is the half-life of PT-141?

Studies have shown that PT-141 has a relatively short half-life of 2 hours. This means that this research chemical is eliminated rather quickly from the body.


What does PT-141 do for men?

In clinical trials involving healthy males as well as those with ED, PT-141 treatment stimulated penile activity in under 30 minutes.


Is PT-141 similar to Viagra?

PT-141 has a much different working mechanism from Viagra, an approved sexual medicine. While Viagra stimulates penile activity by promoting blood flow to the penis, this synthetic peptide acts on the nervous system to potentially treat low sexual desire.


Where to Buy PT-141 for Sale? is the best place to buy PT-141 for sale.

We have been around since 2023, supplying the highest-quality research compounds money can buy. Our products come with a 100% satisfaction guarantee, fast shipping, and great customer service to turn every customer into a repeat customer.



PT-141, also called Bremelanotide, has been found to increase sexual desire and activity in females with various sexual desire disorders. This synthetic peptide has also been reported to induce weight loss in obese females and penile erections in men with erectile dysfunction. sells PT-141 for laboratory and research use only.


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