Buy Cardarine (GW-501516) for Sale
Cardarine, also known as GG-501516, is a PPAR agonist. In a study involving Caucasian men (ages 18 to 50 years), Cardarine reportedly improved multiple metabolic abnormalities, including insulin resistance, oxidative stress, obesity, and dyslipidemia.
Another human study found that Cardarine increased fat burning in men with high belly fat and a poor cholesterol profile. Preclinical studies have reported that GW-501516 could reduce inflammation, improve running endurance, and reduce oxidative stress.
What is Cardarine?
Cardarine is a peroxisome proliferator-activated receptor delta (PPAR-delta) agonist. PPARδ is a type of protein found in the body. It plays a crucial role in regulating energy metabolism, including the breakdown and use of fats and glucose for energy.
GW501516 was developed in the 1990s by Ligand Pharmaceuticals and GlaxoSmithKline as a potential treatment for cardiovascular and metabolic diseases. However, it was never brought to the market due to unpromising results in early rodent studies. [R]
Clinical studies have shown that Cardarine can improve insulin resistance, combat obesity, and enhance fat loss. Human research has further indicated that GW501516 could help burn fat by increasing the oxidation of free fatty acids (FFAs).
In preclinical studies, this PPARδ agonist has demonstrated the ability to improve heart health, enhance running endurance, and decrease inflammation. Additionally, in a mice model of deteriorated kidney function, Cardarine boosted kidney health.
How does Cardarine Work?
Cardarine works by binding to PPARδ, which activates a cascade of events that increase the expression of genes involved in energy metabolism, such as fatty acid oxidation and glucose uptake. This leads to an increase in energy production and improved glucose metabolism. [R]
Additionally, Cardarine has been shown to increase the expression of genes involved in producing the “good” HDL cholesterol and decrease the expression of genes involved in producing the “bad” LDL cholesterol. This can lead to an improved lipid profile. [R]
Cardarine has been the subject of several studies examining its effects on metabolism, endurance, and oxidative stress. Here are some key findings:
1) Cardarine and Metabolism
A study conducted on young Caucasian men between 18 and 40 years has shown that Cardarine treatment could improve several abnormalities linked with metabolic syndrome. These include issues such as high blood fat levels, obesity, and insulin resistance. [R]
It’s worth noting that participants in the study were living in a clinical research facility and were given a standardized diet. Yet, there were no adverse effects reported. Given these promising results, further research on this research chemical is warranted.
2) Cardarine and Fat Burning
According to a study, Cardarine treatment decreased fatty acids and triglycerides in men with high belly fat and a poor cholesterol profile. GW501516 lowered body fat levels by increasing fat utilization in the skeletal muscle tissue and enhancing fat clearance from the body. [R]
A six-week double-blind, placebo-controlled trial backed these effects. It showed that inactive obese men who took GW501516 burned more fat than those who didn’t. This mechanism supports GW501516’s potential use in treating high blood fat levels in people with obesity. [R]
3) Cardarine and Heart Health
A 2007 study showed that Cardarine treatment could boost heart health.
The 12-week trial involved a group of 24 healthy volunteers who were assigned to receive either a placebo, 2.5 mg of Cardarine, or 10 mg of Cardarine. Both the groups who received GW501516 experienced an increase in HDL “good” cholesterol and a reduction in triglycerides. [R]
Preclinical studies have shown that low doses of Cardarine could be beneficial for heart health. At small doses, GW501516 could help unclog the blood vessels, thereby preventing the risk of plaque build-up and resulting in heart disease. [R]
4) Cardarine and Inflammation
Animal studies have highlighted multiple ways Cardarine could suppress inflammation.
For instance, in one mice study, GW501516 lowered the presence of TNF-alpha, an inflammatory cytokine linked to cancer. Similarly, another animal experiment showed that it ameliorated diabetic wounds, which are a result of excessive inflammation. [R] [R]
Additionally, separate investigations involving mice found that Cardarine lowered the levels of IL-6 and NFκB. IL-6 is an inflammatory substance whose high levels are linked to brain damage, whereas nuclear factor kappa beta is associated with cancer and arthritis. [R]
5) Cardarine and Diabetes
In separate preclinical studies, Cardarine exhibited positive effects on gestational diabetes and diabetic wounds. [R]
Gestational diabetes is a condition in which pregnant persons experience high blood sugar. A study involving rats with this condition noted an improvement in blood glucose and insulin levels following treatment with this PPAR-delta agonist.
A separate study found that topical application of GW501516 expedited the healing of diabetic wounds. [R]
6) Cardarine and Endurance
One animal study has shown that GW501516 could improve running endurance.
Results from the study show that Cardarine enhanced running capacity by enhancing the consumption of specific fatty acids and reducing glucose utilization. This is different from how training enhances running capacity, such as by promoting glucose utilization. [R]
7) Cardarine and Oxidative Stress
Preclinical research has shown that GW501516 may lower oxidative stress.
An animal study conducted on GW501516 found that its administration improved blood circulation in the brain and decreased oxidative stress. These findings suggest that Cardarine may exert a neuroprotective effect by shielding brain cells against oxidative stress. [R]
Frequently Asked Questions
Is Cardarine a SARM or Steroid?
Cardarine (GW501516) is not a selective androgen receptor modulator or a steroid. It is a PPAR-delta agonist, a type of medication that enhances the activity of a receptor in the body known as peroxisome proliferator-activated receptor delta.
What is the half-life of Cardarine?
The half-life of Cardarine is approximately 16-24 hours. This means that it takes around one to two days for half of the drug to be eliminated from the body.
Does Cardarine suppress testosterone?
There is currently no evidence to suggest that Cardarine suppresses testosterone levels. In fact, some animal studies have shown that it may actually increase testosterone production.
Is Cardarine legal?
Cardarine is not approved for human use by the US FDA and is classified as a prohibited substance by the World Anti-Doping Agency (WADA). However, it is still available for purchase as a research chemical.
Does Cardarine cause hair loss?
There is currently no evidence to suggest that Cardarine causes hair loss. However, as with any research chemical, more studies are needed to back or refute this assertion.
Does Cardarine cause cancer?
There is conflicting evidence surrounding the potential cancer-causing effects of Cardarine (GW501516). Early studies suggested that it caused cancer in rodents, which is why it was never developed further. However, recent clinical studies have shown that it poses no such risk in humans.
Does Cardarine increase muscle mass?
Currently, no evidence suggests that Cardarine increases muscle gene expression in skeletal muscle cells.
Where to Buy Cardarine for Sale?
Research Chems is the best place to buy GW501516 online.
We have been around since 2023, supplying the highest-quality research compounds money can buy. Our products come with a 100% satisfaction guarantee, fast shipping, and great customer service to turn every customer into a repeat customer.
Cardarine GW-501516 is often lumped with selective androgen receptor modulators even though it’s a PPAR-delta agonist. It has demonstrated the ability to enhance preferential lipid utilization, improve blood cholesterol levels, and reduce inflammation in various studies.
It has also been found to ameliorate various metabolic disorders linked with metabolic syndrome. However, Cardarine GW501516 remains banned for human consumption.
Research Chems sells GW501516 for laboratory and research use only.